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Science and Technology

The AI that does work in medicine: 105,934 women, 29% more cancers detected and half the reading

AI reduces reading workload by nearly half while detecting more breast cancers in MASAI study

Of everything promised about artificial intelligence in medicine, one case has completed the full course: randomised trial, prespecified primary endpoint, published result. It is breast cancer screening, and the trial is called MASAI. With 105,934 women randomised within Sweden's national programme, AI-supported reading detected 29% more cancers than standard double reading, without increasing false positives, and cut reading workload by 44%. And in 2026 came the missing figure: interval cancers, the endpoint that actually measures whether a screening programme is safe. This article explains why this case counts and what sets it apart.The 30-second summary: the seven figures that matterEach…
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ChatGPT to start showing users ads based on their conversations

therapy apps fail to outperform generic ChatGPT in clinical trials

The meta-analyses agree that mental health chatbots reduce symptoms of depression and anxiety. The effect size is around 0.3, which in this literature is modest but real. The problem lies in what emerges when you read the trials one by one. In the trial that compared a purpose-built therapy app against plain ChatGPT, the app did not outperform the generic chatbot on any measure. In the one that followed 540 people for six weeks, the AI version multiplied usage frequency by 2.4 and time spent by 3.8, and symptoms improved just as much as with static workbooks. And in the…
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Rubin Observatory finds possible new dwarf planet beyond Neptune

Rubin Observatory finds possible new dwarf planet beyond Neptune

The object, 2026 ED138, could be one of the largest bodies known in the outer solar system, but its size and status still need confirming.The NSF–DOE Vera C. Rubin Observatory has found its first candidate dwarf planet: an icy body orbiting the Sun beyond Neptune, currently about 46 times farther from the Sun than Earth is. The object, provisionally designated 2026 ED138, was announced on October 27 by the observatory and the International Astronomical Union's Minor Planet Center.Its exact dimensions remain undetermined. Should the highest projections prove accurate, this object will count as one of the most massive entities ever…
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How are fusion projects progressing toward net energy and engineering milestones?

Where is investment flowing outside artificial intelligence technologies

Investment outside artificial intelligence is flowing most visibly into technologies that produce electricity, move it, store it, connect people, and improve health and security. Clean energy dominates the largest publicly tracked totals: the International Energy Agency expects global investment in clean energy technologies and infrastructure to reach about $2.2 trillion in 2025.There is no definitive global top-ten ranking. Industry reports count different things: a purchased electric vehicle, a new semiconductor factory, a venture-capital round, and a power-grid upgrade are not directly comparable. The ten technologies below are therefore major investment magnets, not a precise league table. The order broadly reflects…
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Meet D. rex, the newly crowned giant fungus ‘king’ that measures almost 2 feet tall

Meet the giant fungus Dianjunus rex, China’s newly discovered marvel

Following the extinction of the dinosaurs roughly 66 million years ago, alternative biological organisms adjusted to an evolving globe. A massive mushroom recently discovered in China is providing researchers with fresh perspectives regarding fungal development and the extraordinary biodiversity that still remains unmapped.A newly identified fungus found in the forests of Yunnan province in southwestern China is attracting scientific attention because of its extraordinary size and evolutionary history. Named Dianjunus rex, the species produces upright reproductive structures that can reach approximately 20 inches (50 centimeters) in height and weigh nearly 5 pounds (2.2 kilograms).Its name draws a comparison with Tyrannosaurus…
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Why are mRNA platforms expanding into new therapeutic areas?

how cost and regulation will affect tech adoption by 2030

10 emerging technologies most likely to transform our lives by 2030The technologies most likely to change daily life by 2030 are not necessarily the most dramatic ones. They are the ones moving from laboratories and pilot programs into workplaces, clinics, homes, vehicles, and public infrastructure. Their effects will also depend on cost, regulation, reliability, and who can access them.The following ten technologies stand out for their capacity to enhance wellness, broaden service access, transform labor practices, and remodel the systems relied upon by individuals.1. Artificial intelligence agentsArtificial intelligence is moving beyond answering questions toward completing multistep tasks. An AI agent…
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What are the 10 technological inventions that failed despite being ahead of their time?

10 technological inventions that never reached full production despite being ahead

10 Technological Inventions That Failed Despite Being Ahead of Their TimeBeing first is not the same as being ready for widespread use. An invention can anticipate a lasting need yet fail because it is too expensive, lacks supporting infrastructure, or asks people to change their habits before a clear benefit exists. These ten examples show the difference between a promising idea and a viable product. Some never reached full production; others reached customers but could not sustain a market.1. Charles Babbage’s Analytical EngineDesigned beginning in the 1830s, the Analytical Engine proposed features that resemble those of a general-purpose computer: a…
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What are the 10 most advanced humanoid robots in the world?

The 10 most advanced humanoid robots that can work alongside humans

The most advanced humanoid robots can walk through spaces built for people, handle unfamiliar objects, respond to instructions, or perform useful work alongside humans. No robot excels at all of these tasks. Some are impressive athletes but have limited practical duties; others are less agile yet have completed factory trials. There is also no universally accepted ranking, because companies disclose different amounts of test data and demonstrations do not always reveal how much human assistance was involved.The ten robots below stand out for their engineering, demonstrated capabilities, or progress toward real-world use. Their positions are a guide to the field,…
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The 15 Equations That Changed Human History

The 15 essential equations that defined human history

Introduction: Why Equations MatterEquations are condensed stories about reality. In a handful of symbols, they describe motion, energy, growth, uncertainty, and even the structure of space and time. Unlike inventions that can be seen or touched, equations reshape civilization silently. They guide engineers, physicians, economists, and technologists. The following fifteen equations did more than solve abstract problems—they redirected the course of human history.1. The Pythagorean Theorema² + b² = c² This geometric relationship between the sides of a right triangle became the backbone of architecture, navigation, and engineering. Ancient builders used it to construct temples and pyramids with precision. Today,…
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The 8 Pandemics That Drove the Greatest Medical Advances

The Black Death and the origins of organized public health

1. The Black Death (1347–1351): The Birth of Public HealthThe Black Death, caused by the bacterium Yersinia pestis, killed an estimated 75–200 million people across Europe, Asia, and North Africa. In some European cities, mortality reached 50 percent of the population. The devastation forced societies to rethink how disease spread and how governments should respond.One of the most enduring medical advances was the development of quarantine. The city-state of Venice required ships arriving from affected ports to anchor for forty days before docking. This practice, based on observation rather than scientific understanding, laid the groundwork for organized public health policy.Other…
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